I think we can pay attention in 2 aspects, first: in my opinion if the cultural gap is to “abyssal”, this red flag should be appear early; second: if the risk is to high and the target represent a threat to buyer, the position of the buyer could be a hostile takeover.
“The means justify the end”!!! unfortunately!
And, before the process gain a momentum (understand waste time and money), it led us to corroborate with the importance of a cultural and personal DD as early as possible, before the moment the target’s name exit from a project pipeline.